Organo functionalized graphene with Pd nanoparticles and its excellent catalytic activity for Suzuki coupling reaction

Article abstract of DOI:10.1016/j.apcata.2015.07.018

Synthesis of well distributed palladium nanoparticles (3-7 nm) on organo di-amine functionalized graphene is reported, which demonstrated excellent catalytic activity for Suzuki coupling reaction. Organo functionalized graphene support acted as an excellent host which helped in avoiding "Ostwald ripening" i.e., preventing palladium nanoparticle sintering and because of which the catalyst as a whole showed excellent catalytic activity for Suzuki coupling reaction. The catalytic material was characterized by X-ray diffraction (XRD), Fourier-transfer infrared spectroscopy (FTIR), Raman spectra, X-ray photoelectron spectra (XPS), and Scanning electron microscope (SEM), Transmittance electron microscopy (TEM) analysis. FT-IR revealed that the organic amine functional group was successfully grafted onto the graphene oxide surface. The formation of palladium nanoparticles was confirmed by XPS techniques. The catalytic activity in the coupling reaction using idobenzene was superb with 100% conversion and 98% yield and also activity remained almost unaltered up to six cycles. Typically, an extremely high turnover frequency of 185,078 h-1 or 3,084.64 min-1 is observed in the C-C Suzuki coupling reaction using organo di-amine functionalized graphene as catalyst. Experiments were also conducted under identical conditions to prove heterogeneity of the catalyst.

Full text of DOI:10.1016/j.apcata.2015.07.018

Accepted Manuscript
Title: Organo functionalized graphene with Pd nanoparticles
and its excellent catalytic activity for Suzuki coupling reaction
Author: Surjyakanta Rana Suresh Maddila Kotaiah Yalagala
Sreekantha B. Jonnalagadda
PII:
S0926-860X(15)30070-3
DOI:
Reference:
http://dx.doi.org/doi:10.1016/j.apcata.2015.07.018
APCATA 15467
To appear in:
Applied Catalysis A: General
Received date:
Revised date:
Accepted date:
6-5-2015
30-6-2015
9-7-2015
Please cite this article as: Surjyakanta Rana, Suresh Maddila, Kotaiah Yalagala,
Sreekantha B.Jonnalagadda, Organo functionalized graphene with Pd nanoparticles
and its excellent catalytic activity for Suzuki coupling reaction, Applied Catalysis A,
General http://dx.doi.org/10.1016/j.apcata.2015.07.018
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Organo functionalized graphene with Pd nanoparticles and its excellent
catalytic activity for Suzuki coupling reaction
Surjyakanta Rana, Suresh Maddila, Kotaiah Yalagala and Sreekantha B.
Jonnalagadda*
School of Chemistry & Physics and College of Agriculture, Engineering & Science, University
of KwaZulu-Natal, Durban, South Africa
*Corresponding author: Prof. Sreekantha B. Jonnalagadda School of Chemistry & Physics
College of Agriculture, Engineering & Science, University of KwaZulu-Natal, Durban, South
Africa
Email: jonnalagaddas@ukzn.ac.za
Phone no: +27 31 260 7325/3090
Fax No-+27 31 260 3091
Graphical abstract
Highlights
 Pd(0) on AAPTMS@G an efficient catalyst for Suzuki coupling.
 Pd(0) AAPTMS@G gives 98% yield of biphenyl in 25 min.
 Remarkably stable and active up to six successive cycles.
Abstract
Synthesis of well distributed palladium nanoparticles (3 – 7 nm) on organo di-amine
functionalized graphene is reported, which demonstrated excellent catalytic activity for Suzuki
1

coupling reaction. Organo functionalized graphene support acted as an excellent host which
helped in avoiding “Ostwald ripening” i.e., preventing palladium nanoparticle sintering and
because of which the catalyst as a whole showed excellent catalytic activity for Suzuki coupling
reaction. The catalytic material was characterized by X-ray diffraction (XRD), Fourier-transfer
infrared spectroscopy (FTIR), Raman spectra, X-ray photoelectron spectra (XPS), and
Scanning electron microscope (SEM), Transmittance electron microscopy (TEM) analysis. FT-
IR revealed that the organic amine functional group was successfully grafted onto the graphene
oxide surface. The formation of palladium nanoparticles was confirmed by XPS techniques.
The catalytic activity in the coupling reaction using idobenzene was superb with 100%
conversion and 98 % yield and also activity remained almost unaltered up to six cycles.
Typically, an extremely high turnover frequency of 185,078 h-1 or 3,084.64 min-1 is observed
in the C-C Suzuki coupling reaction using organo di-amine functionalized graphene as catalyst.
Experiments were also conducted under identical conditions to prove heterogeneity of the
catalyst.
Key words: Pd nanoparticle; Di-amine; Graphene oxide; Graphene; Suzuki coupling.
1. Introduction
Over a period of time, several carbon based supports such as graphite, activated carbon,
carbon nanotubes (CNT) and graphene etc. have been developed to suit catalyst loading. In
2

past two decades, among the nanomaterials, CNTs have fascinated the researchers and industry,
due to the amazing scientific and technological implications [1-4]. Wide range of applications
including nano derivative fabrication, highly sensitive and rapid response with short reaction
times are some of the attractions [5-7]. CNTs are considered to be promising nanomaterials for
developing the next generation sensors, but their toxicity to living organisms is of concern [8].
Graphene which is nontoxic, two-dimensional material, having impressive properties, such as
high surface area, high optical and electrical conductivity etc. is considered to be ideal as
catalytic support [9-19]. Graphene oxide (GO) can be prepared from various sources and using
different methods such as chemical vapor decomposition, (CVD) [20], arc discharge [21,22],
Hummers [23], Hummers sonication [24] and wet chemical methods [25]. GO sheet contains
various functional groups such as hydroxyl, epoxy and carboxylic groups. GO sheets can be
chemically modified to have different substituents. The epoxy and carboxylic groups of GO
sheet can be modified using appropriate organic moieties. The residual oxygen hanging group
on chemically modified graphene oxide can serve as an attractive means for further attachment
of the organic moieties. Graphene based complexes and GOs have potential applications in
catalysis, sensor and energy fields. Currently researchers are focusing on the novel metal
nanoparticles due to their mechanical, optical and chemical properties. These nanoparticles
show high activity because of their sizes, shapes and rate of production when compared to the
large particles and gaseous molecules.
Various metal modified supports like TiO2, ZrO2, SiO2, CeO2, Ce–Zr composites including
graphene have been reported in the literature [26]. Organic and inorganic hybrid materials have
added advantages to bind the metal strongly as compared to the normal support materials. The
metal remains bound and does not leach, hence reusable for several cycles. Different metal
modified amine functionalized supports like silica, clay have also been described in the
literature [27]. Recently our group developed Pd(II) modified amine functionalized graphene
3

oxide for oxidation reaction [28]. Among the noble metals, palladium (Pd) found to be more
attractive in the fields of nanotechnology and catalysis. However, size reduction of active metal
particles results in a significant increase of the reactivity due to the high surface-to-volume
ratio of small particles along with a large fraction of active atoms with dangling bonds exposed
to the surface. Earlier reports described the important role of Pd nanoparticles as a catalyst in
the synthesis of many organic and inorganic reactions [29]. Again, prevention of particle
sintering is another important issue. Due to “Ostwald ripening” mechanism, bare particles
without any supports or stabilizers are easily agglomerated, since larger nanoparticles are more
energetically favored than smaller ones generating large clumps that decrease their initial
activity during the reaction. Such agglomeration frequently happens under harsh reaction
conditions. This work describes, the amine functionalized GO sheets stabilizing the Pd
nanoparticles and also supplying adequate electron density to the anchored Pd(0) species to
facilitate the oxidative addition of halobenzene to Pd(0). Additionally, carbon based
nanoparticles show potential properties due to the synergistic effect of metal nanoparticle and
carbon layer [30]. In organic reactions, Suzuki coupling reaction is one of the most powerful
tools to prepare the bi-aryl structures that exist in the many biologically active complexes and
natural products [18]. Consequently, Pd loaded functionalized graphene is ideal for a C-C
coupling reaction.
Herein, we report for the synthesis of Pd nanoparticles (3 - 7 nm) deposited amine
functionalized graphene. Furthermore, its exceptional scope as catalyst for C-C Suzuki
coupling reactions in aqueous medium with excellent yields (98 %) is established. Experiments
also showed that the catalyst is stable, reusable up to six cycles.
2. Materials and methods
2.1. Preparation of GO catalyst:
4

Initially, graphite powder (0.5 g) and NaNO3 (0.5 g) were dissolved in concentrated H2SO4
(23 ml) with stirring for 20 min and the mixture was cooled on ice bath for 2 h. Then, the
reaction mixture was put on hot plate with magnetic stirrer at 40 °C and KMnO4 (6 g)
crystalline powder was added slowly and stirring continued for 70 min. Then, distilled water
(50 ml) was added to the mixture and stirred for further 20 min, followed by H2O2 (30 %) till
the color of the solution changed from dark brown to yellow. Upon the colour change, water
(50 ml) was added and the resulting solution was sonicated over 2 h. The solution was
centrifuged, separated and filtered with double distilled water several times. The product was
dried in a vacuum oven at 100 oC overnight to obtain GO.
2.2. Preparation of Pd (0)-AAPTMS@G catalyst:
GO (1 g) was dissolved in toluene (50 ml) in a conical flask and sonicated for 2 h. [3-(2-
Aminoethylamino)propyl]trimethoxysilane (AAPTMS) (1.68 mmol) (Aldrich) was added to
the above solution and sonicated for further 1 h. Next, powder palladium nitrate (0.46 mmol, 5
wt%) was added to the mixture and stirred for 4 h and 12 mmol of NaBH4 was added and
stirring was continued for further 1 h. The solution was centrifuged and the product was dried
in a vacuum oven at 100 °C overnight to obtain Pd (0)-AAPTMS@G.
2.3. Physico-chemical analytical methods:
The powder X-ray diffraction (XRD) performed on a Bruker D8 Advance instrument,
equipped with an Anton Paar XRK 900 reaction chamber, a TCU 750 temperature control unit
and a CuKα radiation source with a wavelength of 1.5406 nm at 40 kV and 40 mA.
Diffractograms were recorded over the range 15–90° with a step size of 0.5 per second. The
TEM images were viewed on a Jeol JEM-1010 electron microscope. The images were captured
and analysed by using iTEM software. High resolution TEM images were recorded by using
Jeol JEM 2100 Electron Microscope. The SEM measurements were carried out using a JEOL
5

JSM-6100 microscope equipped with an energy-dispersive X-ray analyzer (EDX). Infrared
spectra of the samples were recorded using Fourier transmission infrared (FTIR) spectrometer
(PerkinElmer spectrum 100 series with universal ATR accessory). Raman spectra are collected
on a Perkin Elmer 1200 Fourier Transform Infrared and on a DeltaNu advantage 532™ Raman
Spectrometer (100 mW Nd: YAG laser with an excitation wavelength of 532 nm). The
electronic structure aspects of the samples were investigated using KRATOS apparatus with
Mg, Al, and Cu Kα as X-ray sources by XPS.
2.4. General procedure for Catalytic reaction:
Iodobenzene (1 mmol) was added to the stirring mixture of tripotassium phosphate (0.0018
mmol), phenyl boronic acid (1.2 mmol), and deionized water (20 ml) followed by the addition
of Pd(0)-diamine functionalized graphene(0.05g). The reaction mixture was then stirred at 90
°C for 25 min and extracted with ethyl acetate (Scheme 1). The organic layer was dried with
anhydrous sodium sulfate (Na2SO4) and the resulting mixture was analyzed by gas
chromatography (GC). The catalyst was recovered by the simple centrifugation and washed
extensively with deionized water.
3. Results and Discussion:
The X-ray diffraction spectra of GO and Pd(0)-AAPTMS@G are illustrated in Figure 1.
The pattern at 2  10.75 is the characteristic diffraction peak (002) of GO [31, 32] and the
other peak at 2  42.94 corresponds to the plane of the carbon hexagonal structure (100) [31,
33]. After modification of both organo group and Pd of the GO sheets, the plane shifted (002)
towards the higher angle at 2  23.11, i.e. formation of graphene nano sheets due to the both
sonication [34] and addition of metal borohydride to GO. The peaks appearing at 2 40.11,
46.27 and 68.32 were due to the presence of Pd planes (111), (200), (220). This suggests the
organo group and Pd incorporation onto the GO sheets.
6

The FT-IR spectra of GO, AAPTMS@GO and Pd(0)-AAPTMS@G samples are shown in
Figure 2A (a-c). From this spectra(a), both 3400 cm-1, 1740 cm-1 and 1385 cm-1 peaks were
due to O–H stretching, C=O stretching of –COOH and O-H vibration of C–OH groups
respectively and 1100 cm-1 was due to the epoxy group vibration. The spectra (b & c) show
that peaks for carboxyl groups vanish [35] and only spectra showing N-H stretching at 3371
cm-1 and NH2 bending mode of free NH2 groups at 1638 cm-1 are visible. The peak at 686 cm-
1 was due to the stretching vibration of Si-O-C and strong interaction of Si-O are noticeable at
1100 cm-1 and 1053 cm-1 (Figure 2B) This results confirms that the amine group was modified
by the surface epoxy, hydroxyl and carboxyl groups of graphene materials. In the Figure 2B
(c), the peak at 564 cm-1 was due to Pd-N stretching frequencies [36] confirming that Pd
nanoparticles were bound to the amine group.
The quality and quantity of graphene layers can be investigated using Raman spectroscopy.
The Raman spectra of GO, AAPTMS@GO and Pd(0)-AAPTMS@G are shown in Figure 3. In
these spectra, the entire sample exhibited the characteristic D, G and 2D bands at 1342, 1560
and 2675 cm-1. The conformation of disorder in the sp2-hybridized carbon atoms in graphene
sheets is from D-band of Raman spectra, while G band corresponds to σ-sp2 bonded C-atoms.
In our materials, D band was very small, indicating negligible disorder in the structure of
material. The 2D band gives the information about number of layers is presented in materials
[37-39]. The absence of D-band as well as shapes of 2D-band suggest that after generation of
Pd nanoparticle, the amine functionalized graphene oxide possibly gets converted to single
layer amine functionalized graphene [40].
The SEM images of GO, diamine functionalized graphene oxide, Pd nanoparticle supported
on amine functionalized graphene and higher magnification of nanoparticles are shown in
Figure 4. The amine functionalized graphene consist of randomly aggregated thin sheets
forming a disordered network and also surface roughness increases compared with GO, due to
7

successful exfoliation (Figure 4a & 4b). The spherical Pd nanoparticles were bounded to the
amine group, which obtained in each layer and also on the edges of the graphene sheet are
shown in Figure 4c & 4d).
Energy-dispersive X-ray spectroscopy gives the information on the type of element present
in the particular area. The EDX image of GO and Pd(0)-AAPTMS@G is shown in Figure 5.
From the spectra, it can be seen that only carbon is present in the GO materials (Figure. 5a),
while silicon, carbon, nitrogen, and Pd are present in the Pd(0)-AAPTMS@G sample(Figure.
5b). The SEM-EDX is correlated with the ICP analysis.
TEM image of (a) GO, (b) AAPTMS@GO, (c) Pd (0)-AAPTMS@G, and (d) Higher
magnification of Pd (0)-AAPTMS@G are shown in Figure 6. The successful exfoliation of
graphite oxide converted to single-layer sheet in Figure 6(a). The net-like structure was
appeared after modification of the organic group over the GO surface (Figure. 6b). The black
spots appearing in Figure 6c represent the existence of nanoparticles. The uniform distribution
of nanoparticles on the organic surface is also observable.
The uniform distribution of Pd nanoparticles on the of amine group bonded to the surface
functional group on the single layer graphene is shown in Figure 7a & 7c. The Pd nanoparticle
was stable relative to the basic organic group and facilitates the product formation. The size of
Pd nanoparticles was 3 nm to 7 nm and the average particle size was 5.5 nm (Figure. 7b & 7d).
The size of the nanoparticles can influence the productivity in the coupling reactions. Harada
et al. [41] reported that relatively more active sites exist on the smaller Pd nanoparticles,
leading to better catalytic activity. The TEM of reused catalyst is illustrated in Figure 7e. No
obvious alteration in morphology was observed for Pd nanoparticles after coupling reactions
in used catalyst. The binding energy of Pd 3d5/2 and Pd 3d3/2 corresponds to 335.55 and 340.94
eV is shown in (Figure 7f), which is similar to Pd (0). Hence it can be proposed that the
8

developed particles were nano sized, highly stable, and reusable for better productivity of
coupling products.
Many researchers have reported the C-C coupling reactions in organic solvents and inert
conditions using different catalysts on acidic support. However, there are very few examples
with Pd as catalyst. The C-C coupling reaction over palladium modified montmorillonite
catalyst, at high temperature (150 oC) with reaction time (2-3 h) and 92% yield was reported
[42]. Corral et al., have reported 35 % conversion towards C-C coupling reaction within 3 h in
presence of organic solvent [43]. The inherent disadvantages in these reports were need for
organic solvent, high temperature and longer reaction times. Literature shows that in Suzuki
coupling reaction, many different bases like Na2CO3, Cs2CO3, K2CO3, KF and NaOH were
used in stoichiometric proportions [44]. In the current study Ba(OH)2 or K3PO4 were
successfully employed as a base, with no need to use stoichiometric amounts.
In this communication, we report the use of AAPTMS@GO with basic support. The
catalytic activity of Pd substituted amine functionalized graphene hybrids in the formation of
biaryl C–C bonds was examined for the Suzuki coupling reaction of halobenzene with
phenylboronic acid in the aqueous medium (Scheme 1) which gave excellent yield (98%) with
short reaction time (< 30 min). To compare the activity of the these materials, the reaction was
carried out with GO, AAPTMS@GO Pd(0)-AAPTMS@G and Pd/rGO as a catalysts under
otherwise identical conditions (Table. 1). Results indicate that the C-C coupling reaction
through the reductive elimination process over Pd(0)-AAPTMS@G gave excellent yield, while
others showed poor performance. Oxidative addition of phenyl halides in the presence of
catalyst is the key step in the proposed mechanism (Scheme 2).
A perusal of results in Table 1 clearly show that Ba(OH)2 or K3PO4 as base have facilitated
good yield of cross-coupling reaction product.
We examined the further scope of the method using other halo benzenes and halo pyridines
9

as starting materials (Table. 2). The bond energies of C–Cl, C–Br and C–I bonds are 340.2,
281.4 and 222.6 kJmol-1 respectively. The C-I bond easily breaks and to form C-C product as
compared to other. The Pd (0)-AAPTMS@G catalyst gave relatively lower yields for Cl-
substituents, but was efficient for reactions between Br-substituted pyridines or Br-substituted
benzenes in the C-C coupling giving good yields. Turner et al. have reported that the small
sized Pd nanoparticles give the better catalytic properties [45]. The ability to control the size
of the Pd nanoparticles with basic support onto the amine functionalized graphene is therefore
an advantage of our method. With the aid of basic support, the stability and activity of Pd
nanoparticles on graphene was impressive, possibly due to adequate electron density on
attached Pd (0) species, which accelerated the oxidative addition of halobenzene to Pd (0).
To optimise the catalyst loading, it’s effect on the yield % of biphenyl was studied over
Pd(0)AAPTMS@G was investigated (Figure 8). The yield% increased from 87% to 98% with
increase in the catalyst amount from 0.02 to 0.05 g, but no enhanced yield was recorded with
higher amount of catalyst. 0.06 g gave 98% yield only.
In heterogeneous catalysis, the reusability of the catalyst is paramount and it primarily
depends on the stability and the ease of separation of the catalyst. The activity of catalyst can
change due to the coke formation on the catalyst surface and due to leaching of some
nanoparticles into the reaction medium. Hence to test its robustness, the recovered catalyst was
reused after regeneration by calcination in the reaction for six consecutive cycles. No
noticeable change was observed with activity remaining intact (Table 3). The catalyst did not
leach out in aqueous medium because of the strong interaction between organo amino group
and nanoparticles. The 7th cycle to onwards some reduction in its efficiency was noticed from
ICP analysis. The ICP analysis demonstrates that after five repetitive uses of the catalyst in the
coupling reactions, the decrease in Pd concentration was < 0.8% relative to original sample,
10

suggesting that leaching was negligible, but after the seventh and eighth runs, the leached
amount of Pd was ~10% and ~15 % respectively.
Turnover frequency (TOF) a measure of efficiency of catalyst totally depends on the Pd
concentration, which reflects the structural development of supported palladium. Mulhaupt et
al., reported that Suzuki coupling reaction over Pd2+ exchanged graphite oxide catalyst gives
turnover frequency [TOF = 39000 h−1 (650 min-1)] [46]. Siamaki et al., have observed that
coupling reaction over Pd/G catalyst gave [TOF = 108,000 h-1 (1800 min-1)] [47]. Nie et al.,
reported that Suzuki coupling reaction over Pd–Ni/RGO catalyst gave [TOF = 38,750 h−1
(645.83 min-1)] [48]. In the current study using Pd(0)-AAPTMS@G as catalyst, higher TOF
[185,078 h-1 (3084.64 min-1)] and excellent conversion (100%) up to 6th run were observed for
the C-C Suzuki coupling reaction.
A comparison of various parameters for C-C Suzuki coupling reaction with various reported
catalysts is summarized in Table 3. An examination of the data in table 3 shows that proposed
method proves superior with better TOF, excellent conversions, longer reusability and no need
for solvent, relative to earlier reported catalysts which need organic solvent/ higher reaction
times and short catalyst lives. Through some systems also got excellent results, the use of
organic solvent is not so environmentally benign. Wang et al. have reported the reaction using
ethanol as an organic solvent, with the help of Pd/graphene catalyst and got 100% conversion
[54]. Therefore the effectiveness of our new catalyst in absence of any organic solvent and
high TOF is rewarding.
FT-IR spectra for regenerated catalysts are shown in Figure 9. It can be seen that though
there is a decrease in intensity, the spectra of the reused catalysts are quite similar to that of the
fresh one in figure 2. This confirms the retention of catalyst structure. All these experimental
evidences suggest the catalyst to be truly heterogeneous.
4. Conclusions:
11

In conclusion, the Pd nanoparticles supported on amine functionalized graphene were
successfully prepared by a simple procedure and the catalyst was found to be efficient (98 %
yield), highly stable, reusable and excellent TOF (3084.64 min-1) for C-C coupling reactions.
The Raman study revealed that the catalyst was single layer graphene. As confirmed by the
FTIR and TEM analysis, organic group was covalently bound onto graphene layer. TEM
confirmed that Pd nanoparticles (3 - 7 nm) were uniformly distributed over the surface of amine
functionalized graphene. The recovered catalyst can be reused after regeneration by
calcination.
Acknowledgement
The authors acknowledge the support received from the School of Chemistry & Physics and
College of Agriculture, Engineering & Science, University of KwaZulu-Natal, Durban, South
Africa in the form of research facilities and financial support.
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Scheme 1 Schematic diagram of C-C coupling reaction over Pd (0)-AAPTMS@G catalyst
Scheme 2 Mechanism of C-C coupling reaction over Pd(0)-AAPTMS@G catalyst
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17

List of Figures
Figure 1 XRD spectra of GO (a) and Pd(0)-AAPTMS@G.
Figure 2A FT-IR spectra (4000-400) of GO (a), AAPTMS@GO (b) and Pd(0)-AAPTMS@G
(c) samples.
18

19

Figure 2B FT-IR spectra (2000-400) of GO (a), AAPTMS@GO (b) and Pd(0)-AAPTMS@G
(c) samples.
Figure 3 Raman spectra of GO (a), AAPTMS@GO (b) and Pd(0)-AAPTMS@G (c)
materials.
20

Figure 4 SEM Image of (a) GO, Scale bar = 200 nm (b) AAPTMS@GO, Scale bar = 100
nm, (c) Pd(0)-AAPTMS@G, Scale bar = 2 µm and (d) Higher magnification of Pd(0)-
AAPTMS@G, Scale bar = 200 nm.
21

22

Figure 5 EDX Image of (a) GO, and (b) Pd(0)-AAPTMS@G sample.
Figure 6 TEM Image of (a) GO, scale bar =100 nm (b) AAPTMS@GO, scale bar =100 nm
(c) Pd (0)-AAPTMS@G, scale bar =100 nm and (d) Higher magnification of Pd (0)-
AAPTMS@G, scale bar = 50 nm.
23

24

Figure 7 TEM image of (a) Pd nanoparticles, Scale bar = 50 nm (b) Histogram of the particle
size distribution for the Pd nanoparticles, (c) Pd nanoparticles, Scale bar =100 nm (d)
Histogram of Pd nanoparticles, (e) TEM image of the recycled catalyst, Scale bar = 50 nm and
(f) XPS spectra of Pd nanoparticle.
25

Figure 8 Influence of the catalyst amount on C-C coupling reaction of biphenyl at constant
time, temperature and solvent.
26

Figure 9 FTIR spectra of reused catalyst.
List of Tables
Table-1 Activity of Various Catalysts toward C-C coupling reaction [a].
[a]
Reaction
conditions:
Catalyst
Yield (%)
-----------
11
GO
temperature, 90 °C;
time, 25 minute;
catalyst, 0.05 g;
solvent (water), 20
AAPTMS@GO
27

Pd(II)AAPTMS@GO
Pd(0)AAPTMS@G
Pd/rGO
74
98
96
mL.
iodobenzene
Reactants:
(1
mmol);
phenylboronic acid
(1.2
mmol);
tripotassium
phosphate (0.0018 mmol).
28

Table 2: Effect of different substrate on C-C coupling reaction[a] over Pd (0)-AAPTMS@G
catalyst.
Entry
Substrate
Products
Yield
(%)
1
98
2
79
3
4
5
6
33
96
84
32
43
7
[a]Reaction conditions: temperature, 90 °C; time, 25 minute; catalyst, 0.05 g; solvent (water),
20 ml. Reactants: iodobenzene (1mmol); phenylboronic acid (1.2 mmol); tripotassium
phosphate (0.0018 mmol).
Table 3: Comparison study of C-C coupling reaction catalyzed by Pd(0) in a variety
supported catalysts
29