ORGANOMANGANESE (II) REAGENTS XIX. ACYLATION OF ORGANOMANGANESE CHLORIDES BY CARBOXYLIC ACID CHLORIDES IN THF: A CLEAR IMPROVEMENT IN THE FIELD OF THE PREPARATION OF KETONES FROM ORGANOMANGANESE COMPOUNDS.

Article abstract of DOI:10.1016/S0040-4039(00)70699-X

Organomanganese chloride reagents react with carboxylic acid chlorides, in THF, to give the corresponding ketones in excellent yields.The reaction is of broad scope, it is very interesting from practical and economical point of view since organomanganese chlorides (in THF) are the most stable and cheap organomanganese reagents.With methyl, aryl, alkenyl and s- or t-alkylmanganese chlorides, the acylation is advantageously performed in the presence of a catalytic amount of copper chloride.This new procedure allows to prepare methyl, aryl and alkenylketones as well as s- or t-alkylketones in good yields.