Chemistry - A European Journal p. 18002 - 18009 (2017)
Update date:2022-08-29
Topics:
Piens, Nicola
Goossens, Hannelore
Hertsen, Dietmar
Deketelaere, Sari
Crul, Lieselotte
Demeurisse, Lotte
De Moor, Jelle
Van den Broeck, Elias
Mollet, Karen
Van Hecke, Kristof
Van Speybroeck, Veronique
D'hooghe, Matthias
The reactivity of 3-oxo-β-lactams with respect to primary amines was investigated in depth. Depending on the specific azetidin-2-one C4 substituent, this reaction was shown to selectively produce 3-imino-β-lactams (through dehydration), α-aminoamides (thr
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