Bioorganic and medicinal chemistry letters p. 59 - 64 (1999)
Update date:2022-08-11
Topics:
Han
Cho
Kim
Seo
Moon
Jhon
Several monoacetyldiglycerides were synthesized from glycerol in search for new Ca2+ mobilizing agent in vitro. All monoacetyldiglycerides except linolenoyl and phenlycyclopropylcarbonyl derivatives showed activity toward Ca2+ release in pancreatic acinar cells. Linoleoyl and docosahexaenoyl derivatives were chosen for further test and exhibited unique activity.
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