Total synthesis of R-(+)-patulolide A and R-(-)-patulolide B: The macrolides isolated from Penicillium urticae mutant

DOI: 10.1016/S0040-4020(99)00164-7

Source and publish data:

Tetrahedron p. 5177 - 5184 (1999)

Update date:2022-08-11

Topics:

Authors:

Kalita, Dipak

Khan, Abu Taleb

Barua, Nabin C.

Bez, Ghanashyam

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Article abstract of DOI:10.1016/S0040-4020(99)00164-7

The title compounds (2E,11R)-4-oxo-2-dodecen-11-olide, 1 and (2Z,11R)- 4-oxo-2-dodecen-11-olide, 2 were synthesised in optically pure forms from a nitroalkane synthon involving a chiral resolution step using goat liver lipase.

Full text of DOI:10.1016/S0040-4020(99)00164-7

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