
Synthesis p. 290 - 292 (1993)
Update date:2022-08-16
Topics:
Clay
Collom
Karrick
Wemple
A high yield, economical method for preparation of β-oxo esters has been developed involving the reaction of acid chlorides with potassium ethyl malonate using a magnesium chloride-triethylamine base system in either acetonitrile or ethyl acetate solvents. The method is suitable for the preparation of high purity β-oxo esters in the laboratory and also in large scale production.
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Doi:10.1039/tf9252100202
(1925)Doi:10.1002/adsc.201500952
(2016)Doi:10.1246/bcsj.12.116
(1937)Doi:10.1021/cg200184c
(2011)Doi:10.1016/j.electacta.2009.05.069
(2009)Doi:10.1016/j.bmcl.2016.05.041
(2016)