Synthesis of chiral oxazolidin-2-ones and imidazolidin-2-ones via DMAP- catalyzed isocyanation of amines with di-tert-butyl dicarbonate

DOI: 10.1016/S0040-4039(98)02194-7

Source and publish data:

Tetrahedron Letters p. 9407 - 9410 (1998)

Update date:2022-08-29

Topics:

Authors:

Knoelker, Hans-Joachim

Braxmeier, Tobias

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Article abstract of DOI:10.1016/S0040-4039(98)02194-7

Oxazolidin-2-ones and imidazolidin-2-ones are prepared under mild reaction conditions by DMAP-catalyzed isocyanation of 1,2-aminoalcohols and 1,2-diamines with di-tert-butyl dicarbonate and subsequent cyclization.

Full text of DOI:10.1016/S0040-4039(98)02194-7

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Product name:(R)-4-Benzyl-2-oxazolidinone

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