Biological and Pharmaceutical Bulletin p. 1487 - 1491 (1995)
Update date:2022-08-17
Topics:
Motoki
Morita
Kobayashi
Uchida
Akimoto
Fukushima
Koezuka
Ten kinds of monoglycosylceramides (MonoCers), having the same ceramide portion and different sugar moieties, were synthesized and their immunostimulatory and antitumor activities were examined. The manner of combination between sugar and ceramide has been demonstrated to affect the manifestation of immunostimulatory and resultant antitumor activities of MonoCers, and in the case of D-MonoCers having the D-sugar, α-D-MonoCers (sugar combined to ceramide in an α-configuration) show stronger activities than β-D-MonoCers. Furthermore, the form of sugar, not the furanose-form but the pyranose-form, and the 2- and 4-hydroxyl groups of the pyranose-form of sugar, seemed to play an important role in the manifestation of the activities of α-D-MonoCers.
View More
SHANXI XINTIANYUAN PHARMACEUTICAL CO., LTD.
website:http://www.tychemical.com
Contact:0086-358-3521713 3521715
Address:No. 1 Yintong Road, Shanxi Jiaocheng Economic Development Zone, Xiajiaying Town, Jiaocheng County, Lvliang City, Shanxi Province, China
Contact:86-513-84128750/13773795976
Address:No.48.Youyi West Road ,Rudong Development Zone,Jiangsu Province,China
shanghai jinshan pharmaceutical Co.,Ltd
Contact:021-57363011，13681638167
Address:No. 7966 Tingfeng Road,Jinshan,Shanghai,China
Zhangjiagang Golden Reach Fine Chemical Co.,LTD.
Contact:+86-512-6585 6968
Address:Changfu Road， Dongsha Chemical Industry Park, Zhangjiagang City, Jiangsu Province, China
Jiangsu Haian Petro chemical Plant
Contact:+86-513-88902723
Address:99, Changjiang West Road, Haian County, Jiangsu
Doi:10.1016/j.tetlet.2017.07.088
(2017)Doi:10.1038/183399a0
(1959)Doi:10.1007/s11243-010-9398-2
(2010)Doi:10.14233/ajchem.2013.oh47
(2013)Doi:10.1016/S0040-4039(01)89236-4
(1965)Doi:10.1021/jo00322a022
(1981)
