Direct annulations toward phosphorylated oxindoles: Silver-catalyzed carbon-phosphorus functionalization of alkenes

Article abstract of DOI:10.1002/anie.201209475

Silver screen: The AgNO₃-catalyzed carbon phosphorylation of alkenes occurs by an alkene addition/cyclization cascade. Ag⁺ reacts with Ph₂P(O)H to form the crucial active intermediate 1, which promotes the reaction. This method requires a cheap, nontoxic silver salt as the catalyst and substrates for the transformation are simple and readily accessible.