
Tetrahedron Letters p. 6363 - 6366 (1997)
Update date:2022-08-11
Topics:
Ahman, Jens
Buchwald, Stephen L.
Aryl triflates are coupled with amines using catalytic amounts of Pd(OAc)2 and BINAP and Cs2CO3 as a stoichiometric base. This protocol allows for the efficient amination of electron-poor as well as electron-rich aryl triflates and the reaction conditions are compatible with a wide variety of functional groups.
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