Chemical and Pharmaceutical Bulletin p. 1931 - 1934 (1994)
Update date:2022-08-28
Topics:
Kitagawa
Ito
Tsutsui
The reaction of imidazole (15) with formyl chloride (14), generated in situ by the action of oxalyl chloride (10) on formic acid (3), afforded N-formylimidazole (7), which is a convenient formylating reagent. This procedure was used to prepare N-formyl derivatives (2) of aliphatic, aromatic and heteroaromatic amines (1) under mild conditions.
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