The role of hydrolanes in a synthesis of some epoxyalkyl β-C- cellobiosides

Article abstract of DOI:10.1016/S0040-4020(98)01177-6

An endoglucanase from Humicola insolens has been used to glycosylate a range of alkenyl β-D-C-glucopyranosides with β-lactosyl fluoride. The resulting trisaccharides have been subjected to the action of a commercial β-galactosidase to form alkenyl β-C-cellobiosides. Oxidation of these has given a range of epoxyalkyl β-C-cellobiosides, putative inhibitors of cellobiohydrolases.