Chiral Auxiliaries for Asymmetric Synthesis: Enantioselective Addition of Dialkylzincs to Aldehydes Catalyzed by Chiral 1,2-Disubstituted Ferrocenyl Amino Alcohols

Article abstract of DOI:10.1021/jo00006a048

Chiral 1,2-disubstituted ferrocenyl amino alcohols derived from (R)- and (S)-N,N-dimethyl-1-ferrocenylethylamines 1 and 9 catalyze the enantioselective addition of dialkylzincs to aldehydes to afford optically active S and R secondary alcohols.The degree