Heterocycles p. 145 - 148 (1993)
Update date:2022-08-24
Topics:
Yano, Shin-go
Ohno, Tomoyasu
Ogawa, Kazuo
5-Chloro-4-hydroxy-2(1H)-pyridinone (1) was prepared by 4-step reactions via the key intermediate 5-chloro-3-cyano-4-methoxy-2(1H)-pyridinone (5).This synthetic route has several advantages over the reported methods in procedure, yield and applicability.
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