Tetrahedron Letters p. 457 - 460 (1986)
Update date:2022-08-11
Topics:
Siegel, Craig
Thornton, Edward R.
Very high (> 99percent) diastereofacial selectivities in aldol reactions of a chiral titanium enolate with a variety of aldehydes can be conveniently achieved.The ease of preparation of -Ti(OCHMe2)3 enolates, low cost, low toxicity, and ease of work-up make this a very useful method for synthesis of chirally pure substances.
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(2018)
