Allyl as internucleotide protecting group in DNA synthesis to be cleaved off by ammonia

DOI: 10.1016/0040-4020(95)00344-8

Source and publish data:

Tetrahedron p. 6971 - 6976 (1995)

Update date:2022-08-11

Topics:

Authors:

Bergmann, Frank

Kueng, Erich

Paiza, Patrick

Bannwarth, Willi

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Article abstract of DOI:10.1016/0040-4020(95)00344-8

Deprotection of allyl groups from internucleotide phosphotriester functions can be achieved not only with Pd⁰-mediated cleavage in the presence of an appropriate nucleophile but also under standard conditions for DNA fragments using conc. ammon

Full text of DOI:10.1016/0040-4020(95)00344-8

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