A mild preparation of α-halo-α,β-enones from cyclic enones

Article abstract of DOI:10.1016/S0040-4039(99)01213-7

A simple one pot procedure flor the selective transformation of cyclic enones into α-halo-α,β-enones is reported using dimethyldioxirane and metal halides/Amberlyst 15. The method appears particularly appealing for the preparation of labelled molecules for use with the CMIA technique.