Tetrahedron Letters p. 8621 - 8624 (1998)
Update date:2022-08-17
Topics:
Yang, Zhiqiang
Lorenz, Jon C.
Shi, Yian
An organozinc species RXZnCH2I generated by reacting Zn(CH2I)2 with RXH was found to be an efficient reagent for the cyclopropanation of olefins at room temperature. A 50.7% ee was obtained for the cyclopropanation of trans-β-methylstyrene when a chiral alcohol was used.
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