Tetrahedron p. 4559 - 4574 (1993)
Update date:2022-08-17
Topics:
Hackmann, Claus
Schaefer, Hans J.
A method for the synthesis of γ-butyrolactones 6 is described in which the key step is a free-radical cyclization of α-bromoacetals 4 to 2-alkoxytetrahydrofurans 5 in 54-93percent yield induced by activated chromium(II)-acetate.Four new methods have been developed in order to activate the transition metal.Two of them require only catalytic amounts of chromium(II)-acetate, because it can be regenerated in situ chemically or electrochemically.The diastereoselectivity of the cyclization depends on the substitution pattern of 4 and ranges between 30.4:1 and 1:54.8.
View More
Contact:86-379-63338609
Address:Jiudian Village,Deting Town,Song County,Luoyang
NanJing Rate Biochemicals CO., LTD
Contact:+86-25-84931986
Address:NO. 1 Hongjing Road,Jiangning Science Park,Nanjing,China
website:https://www.sinoshiny.com/products
Contact:+86-20-62802632;62802633
Address:Room 330 GIGCAS Building,No.511 Kehua Street,Tianhe District
Contact:+86-21-38228826
Address:Room 505 Building 2, No 3377 Kangxin Highway, Shanghai, Republic China
Lianyungang Yunbo Chemical Co.,Ltd.
Contact:518-81066110
Address:B907,Dongsheng"Mingdu Square,21-2 East Chaoyang Road,Xinpu,(sale department)
Doi:10.1016/S0022-328X(00)81957-9
(1982)Doi:10.1021/jo070923d
(2007)Doi:10.1021/j100301a003
(1987)Doi:10.1021/jp057104m
(2006)Doi:10.1039/C6SC03838G
(2017)Doi:10.1016/S0040-4039(00)79709-7
(1991)
