Asymmetric Carbene C-O Insertion Using Optically Active Bipyridine-Copper Complex as a Catalyst. Ring Expansion of Oxetanes to Tetrahydrofurans

Article abstract of DOI:10.1246/cl.1994.1857

Copper complex of (7R,7R')-di(1-t-butyldimethylsiloxy-1-methylethyl)-6,6',7,7'-tetrahydro-5H,5'H-2,2'-bi-1,1'-pyridine (3) was found to be an effective catalyst for asymmetric carbene insertion reaction into the C-O bond of oxetanes.For example, the react