Acylshikonin analogues: Synthesis and inhibition of DNA topoisomerase-I

DOI: 10.1021/jm00006a025

Source and publish data:

Journal of Medicinal Chemistry p. 1044 - 1047 (1995)

Update date:2022-08-25

Topics:

Authors:

Ahn Ahn

Baik Baik

Kweon Kweon

Lim Lim

Hwang Hwang

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Article abstract of DOI:10.1021/jm00006a025

Compounds bearing an acyl group of a various size at 1'-OH of shikonin were synthesized as acyl analogues of shikonin, which was isolated from the root of Lithospermum erythrorhizon, and evaluated for inhibitory effect on topoisomerase-I activity. A selec

Full text of DOI:10.1021/jm00006a025

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