
Tetrahedron Asymmetry p. 739 - 744 (1995)
Update date:2022-08-12
Topics:
Iuliano
Pini
Salvadori
The aminoalcohols (1R)-2-N[(R)-1-phenylethyl]amino-1-phenylethanol, (1R)-2-N[(S)-1-phenylethyl]amino-1-phenylethanol, and (1R)-2-N-methyl-N[(R)-1-phenylethyl]amino-1-phenylethanol, synthesized by simple procedures, have been used as chiral catalysts in the enantioselective addition of diethylzinc to arylaldehydes, obtaining optically active 1-arylpropanols in good chemical yields (47 to 95%) and e.e.s. up to 88%.
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(2020)