Chain carbonylation of methoxymethyl chloride by using AgSbF6 catalyst under high pressure of CO

Article abstract of DOI:10.1016/0040-4020(95)00685-2

The chain carbonylation of methoxymethyl chloride (1) by the use of AgSbF₆ catalyst smoothly proceeded under high pressure of carbon monoxide to give methyl methoxyacetate after treatment with methanol. The reaction was highly dependent on the CO pressure and the reaction temperature, indicating the presence of equilibrium processes. From the temperature dependence of the equilibrium constant, the enthalpy change of the reaction was calculated to be -25.4 kJ mol^-1.