The application of tunable tridendate P-based ligands for the Ru(II)-catalysed transfer hydrogenation of various ketones

Article abstract of DOI:10.1002/aoc.3202

Two novel versatile tridendate aminophosphine-phosphinite and phosphinite ligands were prepared and their trinuclear neutral ruthenium(II) dichloro complexes were found to be effective catalysts for the transfer hydrogenation of various ketones in excellent conversions up to 99% in the presence of 2-propanol/NaOH in 0.1M isopropanol solution. Particularly, [Ru3 (PPh₂OC₂H₄)₂N-PPh₂ (η⁶-p-cymene)₃Cl₆] acts as an excellent catalyst giving the corresponding alcohols in excellent conversion up to 99% (turnover frequency ≤ 1176 h^-1). A comparison of the catalytic properties of the complexes is also discussed briefly. Furthermore, the structures of these ligands and their corresponding complexes have also been clarified using a combination of multinuclear NMR spectroscopy, infrared spectroscopy and elemental analysis. ¹H-¹³C HETCOR or ¹H-¹H COSY correlation experiments were used to confirm the spectral assignments.