Anti-inflammatory, analgesic and antipyretic 4,6-disubstituted 3-cyanopyridine-2-ones and 3-cyano-2-aminopyridines

DOI: 10.1016/0223-5234(92)90141-M

Source and publish data:

European Journal of Medicinal Chemistry p. 627 - 632 (1992)

Update date:2022-08-04

Topics:

Authors:

Manna Manna

Chimenti

Bolasco Bolasco

Filipelli

Palla Palla

Filippelli

Lampa Lampa

Mercantini

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Article abstract of DOI:10.1016/0223-5234(92)90141-M

3-Cyano-4-(R,R'-aryl)-6(2-hydroxyphenyl)-2-(1H)pyridones 2a-o and 3-cyano-4-(R-R'-aryl)-6-(2-hydroxyphenyl)-2-aminopyridines were synthesized which showed anti-inflammatory and analgesic activity. Electron withdrawing substituents in 2' or 4' position on

Full text of DOI:10.1016/0223-5234(92)90141-M

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