An Enzyme-scissile Linker for Solid-phase Peptide Synthesis

DOI: 10.1039/c39920001033

Source and publish data:

Journal of the Chemical Society. Chemical communications p. 1033 - 1034 (1992)

Update date:2022-08-16

Topics:

Authors:

Elmore, Donald T.

Guthrie, David J. S.

Wallace, Andrew D.

Bates, Stephen R. E.

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Article abstract of DOI:10.1039/c39920001033

We describe a new linker that contains a phosphodiester moiety for solid-phase peptide synthesis; after completion of the cycle of coupling and deprotection steps, the phosphodiester can be cleaved with phosphodiesterase.

Full text of DOI:10.1039/c39920001033

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