Tetrahedron Letters p. 2673 - 2676 (1999)
Update date:2022-08-25
Topics:
Poss, Andrew J.
Shia, George A.
1-Fluoro-4-hydroxy-1,4-diazoniabicyclo[2.2.2]octane bis(tetrafluoroborate), NFTh, is a electrophilic fluorinating that can be used to fluorinate aromatic rings, olefins, dienol acetates and enol ethers. When NFTh is reacted with an active methylene compound in the presence of ZnCl2, the corresponding mono- or di-fluoro derivative can be isolated.
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