Total Synthesis of (+)-Kifunensine, a Potent Glycosidase Inhibitor

DOI: 10.1039/P19930001095

Source and publish data:

Journal of the Chemical Society. Perkin transactions I p. 1095 - 1098 (1993)

Update date:2022-08-24

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Authors:

Rouden, Jacques

Hudlicky, Tomas

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Article abstract of DOI:10.1039/P19930001095

(+)-Kifunensine, a potent inhibitor of mannosidase I, has been synthesized in 13 steps from chlorobenzene by microbial oxygenation with Pseudomonas putida 39D and stereocontrolled peripheral functionalization of cis-3-chlorocylohexa-3,5-dienediol 3.

Full text of DOI:10.1039/P19930001095

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