
Journal of Organic Chemistry p. 352 - 355 (2006)
Update date:2022-08-28
Topics:
Ding, Rui
Katebzadeh, Kambiz
Roman, Lisa
Bergquist, Karl-Erik
Lindstroem, Ulf M.
Significant rate acceleration of metal-catalyzed Michael addition reactions in water was observed upon addition of small, dibasic ligands. Ytterbium triflate and TMEDA was the most effective combination leading to a nearly 20-fold faster reaction than in the absence of ligand.
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