
Tetrahedron p. 6693 - 6702 (1986)
Update date:2022-08-17
Topics:
Bonjoch, Josep
Boncompte, Fontsanta
Casamitjana, Nuria
Bosch, Joan
The first synthesis of an indolo<4,3-δg>morphan system has been achieved through a route involving the acid-catalyzed cyclization of a 3-(tetrahydro-2-pyridyl)indoline.A procedure for the reduction of 3-(tetrahydropyridyl)indoles to the corresponding indolines, consisting in the formation of the tetrahydropyridine-borane complex followed by treatment with ethanolic hydrochloric acid, is established.
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