Selective acidic cleavage of ketals in the presence of tert.-butyldimethylsilyl ethers

Article abstract of DOI:10.1080/00397919508011426

Dilute methanolic HCl in anhydrous THF (<0.5% CH₃OH, ca. 10^-2 molar H⁺) cleaves acetals and ketals, whereas t-butyldimethylsilyl ethers where recovered unchanged even at elevated temperatures.

Full text of DOI:10.1080/00397919508011426

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Synthetic Communications: An
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Selective Acidic Cleavage of
Ketals in the Presence of tert-
Butyldimethylsilyl Ethers
K. Zimmermann a b
a Institut f. Organische Chemie, Univ. Wien
Währingerstr. 38 , A-1090, Wien, Austria
b Inst. organic Chemistry. ETH Zurich,
Universitätsstr. , 16, CH-8092, Zurich, Switzerland
Published online: 16 Feb 2007.
To cite this article: K. Zimmermann (1995) Selective Acidic Cleavage of Ketals
in the Presence of tert-Butyldimethylsilyl Ethers, Synthetic Communications: An
International Journal for Rapid Communication of Synthetic Organic Chemistry, 25:19,
2959-2962, DOI: 10.1080/00397919508011426
To link to this article: http://dx.doi.org/10.1080/00397919508011426
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