Synthesis and receptor affinities of some conformationally restricted analogues of the dopamine D1 selective ligand (5R)-8-chloro-2,3,4,5-tetrahydro-3-methyl-5-phenyl-1H-3-benzazepin-7-ol

DOI: 10.1021/jm00128a038

Source and publish data:

Journal of Medicinal Chemistry p. 1913 - 1921 (1989)

Update date:2022-08-17

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Authors:

Berger Berger

Chang Chang

Clader Clader

Hou Hou

Chipkin Chipkin

McPhail McPhail

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Article abstract of DOI:10.1021/jm00128a038

The synthesis of a structurally novel series of 6,6a,7,8,9,13b-hexahydro-5H-benzo[d]naphtho[2,1-b]azepines (2), conformationally restricted analogues of the dopamine D₁ antagonist (5R)-8-chloro-2,3,4,5-tetrahydro-3-methyl-5-phenyl-1H-3-benzazep

Full text of DOI:10.1021/jm00128a038

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