Synthesis of novel intranuclear diazasteroids

Article abstract of DOI:10.1016/0039-128X(95)00093-6

By use of the aza Diels-Alder reaction a series of aminoisoquinolines and aminoquinolines have been elaborated to provide an effective synthesis of diverse diazasteroids. In particular, representative 1, 11-diaza-, 3, 11- diaza-, and 4,11-diazasteroids have been synthesized from cyclopentadiene. From dihydropyran a 4, 11-diaza-15-oxa-D-homosteroid has been obtained.