Tetrahedron Letters p. 2153 - 2154 (1997)
Update date:2022-08-11
Topics:
Adger, Brian M.
Dyer, Ulrich C.
Lennon, Ian C.
Tiffin, Peter D.
Ward, Simon E.
An efficient synthesis of racemic tert-leucine from trimethylpyruvic acid using a Leuckart type reaction is described. A facile resolution of an intermediate with α-methylbenzylamine allows entry into either (R)- or (S)-tert-leucine.
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Doi:10.1016/S0040-4039(00)71374-8
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(1997)
