SYNTHETIC AND NMR SPECTROSCOPIC STUDIES ON THE 2,1,3-BENZOPHOSPHADIAZINE RING SYSTEM

Article abstract of DOI:10.1016/0022-328X(87)80396-0

Alkylation reactions of 2,3-dihydro-2-mercapto-2,1,3-benzophosphadiazine-4(1H)-thione-2-sulphide are described; reaction with methyl iodide occurs sequentially to produce mono-, di-, and tri-methylated derivatives.Reaction of 1,2-dihydro-1-methyl-2,4-bis(methylthio)-2,1,3-benzophosphadiazine with p-chloroaniline leads to a product formed by displacement of SMe groups both from carbon and phosphorous.Lawesson's reagent reacts with o-aminobenzamide to yield 1,2-dihydro-2,4-bis(p-methoxyphenyl)-2,1,3-benzophosphadiazine-2-sulphide.Details of 13C and 31P NMR used to identify these compounds are discussed.