Resolution of alkyl pyridyl sulfoxides by complexation with a chiral host compound derived from tartaric acid

Article abstract of DOI:10.1016/S0957-4166(97)00276-0

Alkyl pyridyl sulfoxides 2 were prepared in high enantiomeric excess by resolution through inclusion complexation with a chiral host compound, (2R,3R) or (2S,3S)-(-)-trans-4,5-bis(hydroxydiphenylmethyl)-2,2-dimethyl-1,3-dioxolane 1. The X-ray crystallographic structure analysis of complex (R,R)-(-)-1 and (R)-(-)-2b is reported.