A chemoselective approach to functionalize the C-10 position of 10- deacetylbaccatin III. Synthesis and biological properties of novel C-10 Taxol analogues

DOI: 10.1016/S0040-4039(00)77242-X

Source and publish data:

Tetrahedron Letters p. 5543 - 5546 (1994)

Update date:2022-08-11

Topics:

Authors:

Kant Kant

O'Keeffe

Chen Chen

Farina Farina

Fairchild

Johnston

Kadow Kadow

Long Long

Vyas Vyas

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Article abstract of DOI:10.1016/S0040-4039(00)77242-X

A chemoselective approach to functionalize the C-10 position of 10- deacetyl baccatin III, a key intermediate for the semi-synthesis of paclitaxel, is described. The chemistry provides an easy access to a variety of C-10 hydroxyl derivatives, such as, eth

Full text of DOI:10.1016/S0040-4039(00)77242-X

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