γ-1,4 Addition of substituted methoxyallylcopper reagents to methylvinylketone

Article abstract of DOI:10.1016/S0040-4039(99)00485-2

Methoxyallylcopper reagents substituted in α and/or β position of methoxy group reacted regiospecifically with MVK to give γ-1,4 adducts, i.e. ketoenolethers, γ substituted methoxyallylcopper reagents gave mixtures of γ-1,4 and α-1,4 adducts.