Mise en evidence d'une reactivite specifique des trifluoromethylcetones vis-a-vis du bromure d'allylmagnesium

Article abstract of DOI:10.1016/0022-1139(94)03097-J

We wish to report on an unusual reactivity of allylmagnesium bromide.This Grignard reagent acts as a reducing agent towards trifluoromethylated ketones.A single electron transfer is suggested to explain the reductive process.By using an excess of allylmagnesium bromide, an exclusive addition reaction is obtained.The stereochemistry of both addition and reduction reactions is discussed. - Keywords: Trifluoromethyl ketones; Trifluoromethyl alcohols; Allylmagnesium bromide; Single electron transfer; Stereochemistry; NMR spectroscopy; IR spectroscopy; Mass spectrometry