Bioorganic and Medicinal Chemistry Letters p. 1525 - 1530 (1997)
Update date:2022-08-11
Topics:
Mantegani, Sergio
Brambilla, Enzo
Cremonesi, Paolo
Caccia, Carla
Fornaretto, Maria Gioia
Carfagna, Nicola
Colombo, Monica
McArthur, Robert A.
Varasi, Mario
A class of (E) and Q-3-styrylpiperidine derivatives was prepared as racemates and evaluated for affinity at σ binding sites labeled with [3H]-(±-SKF-10,047. Some of these compounds exhibited high affinity and selectivity for σ verus D1 and D2 binding sites.
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(1946)
