A facile base-mediated synthesis of N-alkoxy-substituted benzimidazoles

DOI: 10.1016/j.tet.2017.06.063

Source and publish data:

Tetrahedron p. 4811 - 4821 (2017)

Update date:2022-08-11

Topics:

Authors:

Ansari, Nurul H.

Jordan, Arica L.

S?derberg, Bj?rn C.G.

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Article abstract of DOI:10.1016/j.tet.2017.06.063

Base mediated cyclization of enamines derived from condensation of 2-nitroanilines with α-branched aldehydes, in the presence of an electrophile, affords N-alkoxy-substituted benzimidazoles with or without an oxygenate side chain in the 2-position.

Full text of DOI:10.1016/j.tet.2017.06.063

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