Chiral, bicyclic proline derivatives and their application as ligands for copper in the catalytic asymmetric allylic oxidation of olefins

Article abstract of DOI:10.1016/0040-4039(96)01664-4

The preparation of the unnatural, bicyclic α-amino acids 7 and 8 is described, along with their utility as chiral ligands in the copper-catalyzed enantioselective allylic oxidation of cyclohexene with tert-butyl perbenzoate. These bicyclic amino acids wer