Page 3 of 4
Journal Name
ChemComm
COMMUNICATION
DOI: 10.1039/C5CC02155C
yield was obtained for electronꢀrich arenes, such as 4ca (36%).
The current protocol provides the higher yield of 4ca (72%).
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Table 3. Reaction of oꢀArylaminoꢀAcetophenoneꢀoximes with DAST
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(
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4
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.
.
1
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(
,
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2
̈
,
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The scope of the protocol was further expanded towards the 6. (a) P. B. Moya, F. C. Escribano, M. G. Guill6n, F. M. Dfaz,
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E
,
1
5
,
methylbenzoxazole
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6
is formed as the sole product in 41%
,
,
,
8
7
.
,
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, 8,
7
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In conclusion, we have developed a novel protocol as the
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first
example
of
DASTꢀpromoted
Beckmann
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rearrangement/intramolecular cyclization reaction of acyclic
ketoximes, which represents a facile and efficient route to 2ꢀ
oxazolines, benzimidazoles and benzoxazoles. Efforts toward
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in due course.
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2
Notes and references
8
.
a
,
,
Department of Chemistry, Northeast Normal University, Changchun
,
1
30024, China; Eꢀmail: lixq653@nenu.edu.cn
b
,
Department of Chemistry and Environmental Science, Jinzhou Teachers
Training College, Jinzhou 121000, China.
,
1
4
†
Electronic Supplementary Information (ESI) available: Experimental
1
13
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Nishigaki, Chemical compounds. WO 02/44156(A2), June 6, 2002;
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