Mono- and Dialkylation of Derivatives of (1R,2S)-2-Hydroxycyclopentanecarboxylic Acid and -cyclohexanecarboxylic Acid via Bicyclic Dioxanones: Selective Generation of Three Contiguous Stereogenic Centers on a Cyclohexane Ring

DOI: 10.1002/hlca.19890720410

Source and publish data:

Helvetica Chimica Acta p. 690 - 714 (1989)

Update date:2022-08-05

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Authors:

Herradon, Bernardo

Seebach, Dieter

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Article abstract of DOI:10.1002/hlca.19890720410

Ethyl (1R,2S)-2-hydroxycyclopentanecarboxylate and -cyclohexanecarboxylate (1a and 2a, respectively) obtained in 40 and 70 percent yield by reduction of 3-oxocyclopentanecarboxylate and cyclohexanecarboxylate, respectively (Scheme 2), with non-fermenting

Full text of DOI:10.1002/hlca.19890720410

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