Effects of Carbon-Bound Deuterium on the Affinities of Acetaldehyde-1-d and N-Methylformamide-1-d for Solvent Water

Article abstract of DOI:10.1021/ja00342a009

With deuterium present in the formyl group, the equilibrium constant for transfer of N-methylformamide from chloroform to D2O at 25 deg C was encanced by factor of 3.1 +/- 0.15 percent, as estimated independently by proton magnetic resonance and by double-labeling experiments in which 14C and 3H were incorporated alternatively into the methyl group.The distribution coefficient of acetaldehyde-1-d between D2O and the vapor phase, on the other hand, differed from that of acetaldehyde by less than 0.5percent.