AN EFFICIENT SYNTHESIS OF CHIRAL, NONRACEMIC ISOPROPYL ALKENYLMETHYLPHOSPHINATES VIA PALLADIUM ROUTE

Article abstract of DOI:10.1016/S0040-4039(00)95287-0

Enantiomerically pure (S)- and (R)-isopropyl alkenylmethylphosphinates were obtained from the reaction of (R)- and (S)-isopropyl methylphosphinates, respectively, with alkenyl bromides via palladium-catalyzed formation of carbon-phosphorus bond.