New chiral blocks for introducing the side chain of HMG-CoA reductase inhibitors

DOI: 10.1016/S0040-4039(00)74684-3

Source and publish data:

Tetrahedron Letters p. 4183 - 4186 (1992)

Update date:2022-08-04

Topics:

Authors:

Urabe Urabe

Matsuka Matsuka

Sato Sato

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)74684-3

A couple of versatile building blocks (8 and 9) of the side chain portion found in many HMG-CoA reductase inhibitors have been prepared. The successful introduction of the side chain to an aromatic ring by 8 or 9 has been demonstrated.

Full text of DOI:10.1016/S0040-4039(00)74684-3

Products guided by the article

Product name:[(4S,6R)-2,2-Dimethyl-6-((E)-styryl)-[1,3]dioxan-4-yl]-acetic acid tert-butyl ester

Cas No:123185-86-4

R&D Labs maybe for 123185-86-4

Ningbo Distant Chemicals Co.,Ltd

Contact:86-574-27862490,27862438

Address:5F-3,#54 DaShaNi street,Ningbo,CHINA
Hebei Lead Bio-Chemicals Co., Ltd.

website:http://www.ldbiochem.com

Contact:+86-311-87826503

Address:481, Heping West Road, Shijiazhuang,China
Xiamen Goodhealth Pharmchem Co., Ltd.

Contact:0086-592-2097683

Address:404R No.2 54# Minzu Rd., Xiamen, China
U-Chemo Holding Co.,Limited

website:http://www.u-chemo.com

Contact:+86-21-61558312

Address:Dong Fang Road,
Wuhan Konberd Biotech Co., Ltd.

Contact:+86-27-87205925

Address:NO.666, Gaoxin Road, Eastlake High-tech zone

Relevant to this article

Synthesis, characterization and structures of cyclic organorhodium complexes of the type [Rh{CH(SO₂Ph)CH₂CH ₂YR₂-κC,κY}L₂] (YR₂ = PPh₂, NMe₂; L₂ = diphosphine, cyclooctadiene)

Doi:10.1039/c001452d
(2010)
Molecular structure-thermal behaviour relationship of dimers consisting of different terminal substituents and sulphur-sulphur linking group

Doi:10.1016/j.molstruc.2014.03.071
(2014)
Catalyst- and Oxidant-Free Desulfonative C?P Couplings for the Synthesis of Phosphine Oxides and Phosphonates

Doi:10.1002/adsc.201700886
(2017)
Application of desymmetrization protocol for the formal total synthesis of emericellamide B

Doi:10.1016/j.tetlet.2010.04.015
(2010)
2,3-disubstituted indoles via palladium-catalyzed reaction of 2-alkynyltrifluoroacetanilides with arenediazonium tetrafluoroborates

Doi:10.1021/ol101321g
(2010)
NEUE TRIANOLINTHIONE DURCH KOHLENWASSERSTOFF-ELIMINIERUNG AUS TETRASUBSTITUIERTEN TRIAZOLIDINTHIONEN

Doi:10.1016/S0040-4039(01)80401-9
(1989)

Article Doi