Tetrahedron Letters p. 8881 - 8884 (1998)
Update date:2022-08-25
Topics:
Lin, Gialih
Lin, Wen-Yuan
Shieh, Chuen-Tzwu
The enantioselectivity of porcine pancreatic lipase-catalyzed resolution of 1-indanol was enhanced up to 3 fold in the presence of carbamates. The optimum incubation time for 4-nitrophenyl-N-hexyl carbamate and the enzyme was 18 h before this biocatalytic resolution. The optimum concentration of the inhibitor 4-nitrophenyl-N-hexyl carbamate in this resolution was 1% mole equivalent of the substrate 1-indanol.
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