Asymmetric synthesis of 2-methyltaurine

Article abstract of DOI:10.1016/0957-4166(96)00080-8

Enantiomeric (R)- and (S)-2-aminopropanesulfonic acids, 4a and 4b, were prepared in good yields and high enantiomeric purities (> 99% ee) from (S)-5a and (R)-1-amino-2-propanol 5b respectively, using a four step synthesis. The absolute configuration of (S)-enantiomer 4b was established by X-ray analysis.