A synthesis of the C16-C23 segment of FK-506

DOI: 10.1016/0040-4039(90)80037-M

Source and publish data:

Tetrahedron Letters p. 1637 - 1640 (1990)

Update date:2022-08-11

Topics:

Authors:

Stocks Stocks

Kocienski

Donald Donald

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Article abstract of DOI:10.1016/0040-4039(90)80037-M

A copper-catalysed migratory insertion reaction was used to construct the tri-substituted alkene of the C16-C23 segment 4 of the potent immunosuppressant FK-506 (Tsukubaenolide) (1).

Full text of DOI:10.1016/0040-4039(90)80037-M

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